434625

Leukotriene B₄

≥97% (HPLC), oil, proinflammatory agent, Calbiochem^®

• 別名: Leukotriene B₄, LTB₄, 5(S),12(R)-Dihydroxy-6- cis-8- trans-10- trans-14- cis-eicosatetraenoic Acid
• 実験式（ヒル表記法）: C₂₀H₃₂O₄
• CAS番号: 71160-24-2
• 分子量: 336.47
• MDL番号: MFCD00135630
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• product name: Leukotriene B₄, Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium.
• 品質水準: 100
• アッセイ: ≥97% (HPLC)
• 形状: oil
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: clear
• 溶解性: ethanol: soluble
• 輸送温度: wet ice
• 保管温度: −70°C
• InChI: 1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6+,14-10+,15-11+
• InChI Key: VNYSSYRCGWBHLG-XUOUMLBJSA-N

詳細

詳細

Potent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.

Potent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Polymorphonuclear leukocytes

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Flammable (J)

物理的形状

In Ethanol.

再構成

Following initial thaw, aliquot and freeze (-70°C).

その他情報

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem.266, 24763.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H319
• 注意書き: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2