353905

Glutathione Monoethyl Ester

>90% (TLC), solid, GSH-MEE transport, Calbiochem^®

• 別名: Glutathione Monoethyl Ester, γ-GCE, L-γ-Glutamyl-L-cysteinyl Ethyl Glycinate, GSH-MEE
• 実験式（ヒル表記法）: C₁₂H₂₁N₃O₆S
• CAS番号: 118421-50-4
• 分子量: 335.38
• UNSPSCコード: 12352209
• NACRES: NA.77

特性

• product name: Glutathione Monoethyl Ester, Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH.
• 品質水準: 100
• アッセイ: >90% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic)
• 色: white
• 溶解性: water: 50 mg/mL
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
• InChI Key: JKRODHBGNBKZLE-YUMQZZPRSA-N

詳細

詳細

Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases thereby increasing intracellular GSH concentration in many tissues and cell types. Effective transport of GSH-MEE has been used to protect cells against radiation damage, oxidants and various toxic compounds including heavy metals. A protective agent against cellular damage, such as cataracts and mitochondrial degeneration.

Cell-permeable derivative of glutathione (GSH) that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH-MEE has been used to protect cells against damage from radiation, oxidants, and various toxic compounds including heavy metals. A protective agent against cellular damage such as in cataracts and mitochondrial degeneration.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Effective transport of GSH-MEE

Product does not compete with ATP.

Reversible: no

包装

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

再構成

Following reconstitution, aliquot and freeze (-20°C). Unstable in solution; reconstitute just prior to use.

その他情報

Grattagliano, I., et al. 1995. J. Pharmacol. Exp. Ther. 272, 484.
Martensson, J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 317.
Anderson, M.E., and Meister, A. 1989. Anal. Biochem. 183, 16.
Anderson, M.E., et al. 1985. Arch. Biochem. Biophys. 239, 538.
Wellner, V.P., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 4732.
Puri, R.N., and Meister, A. 1983. Proc. Natl. Acad. Sci. USA 80, 5258.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable