23-033-M

MDM2 (c-Myc tagged) Protein, active, 10 µg

Active, full length, recombinant human MDM2. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as an E3 ligase in ubiquitination assays.

• 別名: Double minute 2 protein, p53-binding protein Mdm2, Hdm2
• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.41

特性

• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in E. coli
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable
• GenBankアクセッション番号: AF527840

詳細

詳細

MDM2 is an E3 ubiquitin ligase that regulates the turnover of several cellular factors including the p53 tumour suppressor protein and notably MDM2 itself. The suppression of p53 activity by an amplified Mdm2 gene has been observed in many tumours, including soft tissue sarcomas, osteosarcomas and breast tumours.

N-terminal GST-tagged, recombinant human TRAF6 full length, expressed in E.coli.

アプリケーション

Ubiquitination Cascade Comoponent: E3

物理的形状

Purified using glutathione sepharose followed by gel filtration.

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

GenBank is a registered trademark of United States Department of Health and Human Services

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H317
• 注意書き: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• 危険有害性の分類: Skin Sens. 1
• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable