216100-M

Carboplatin

An analog of Cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.

• 別名: Carboplatin, cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
• 実験式（ヒル表記法）: C₆H₁₂N₂O₄Pt
• CAS番号: 41575-94-4
• 分子量: 371.25
• MDL番号: MFCD00070464
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• 詳細: Merck USA index - 14, 1822
• アッセイ: ≥98% (HPLC)
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: water with 5% glucose: 10 mg/mL
• 保管温度: 10-30°C
• SMILES記法: [Pt]1OC(=O)C2(CCC2)C(=O)O1.[N+H4].[N+H4]
• InChI: 1S/C6H8O4.2H3N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H3;/q;;;+2
• InChI Key: OLESAACUTLOWQZ-UHFFFAOYSA-N

詳細

詳細

An analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.


Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.

An analog of cisplatin with reduced nephrotoxicity. Displays potent antitumor activity.



Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.

生物化学的／生理学的作用

Primary Target
Potent antitumor activity

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Hall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08,GHS07
• シグナルワード: Danger
• 危険有害性情報: H302 + H312 + H332,H317,H334,H340,H360
• 注意書き: P202 - P261 - P280 - P301 + P312 - P302 + P352 + P312 - P308 + P313
• 危険有害性の分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable