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由来生物
human
品質水準
リコンビナント
expressed in baculovirus infected Sf21 cells
製品種目
Upstate®
比活性
(For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
分子量
Mw 39.9 kDa
精製方法
(Ni2+/NTA-agarose)
化学種の反応性
human
メーカー/製品名
Upstate®
テクニック
activity assay: suitable (kinase)
アクセッション番号
(FUNCTION: SwissProt: P52333 # Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K. )
NM_000215.2
NCBIアクセッション番号
UniProtアクセッション番号
詳細
N-terminal His6-tagged, recombinant, human JAK3 amino acids 781-end
アプリケーション
Research Category
炎症及び免疫
炎症及び免疫
生物化学的/生理学的作用
Protein Target: JAK3
Target Sub-Family: TK
包装
Also available in 10 μg size and in bulk
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-629M when ordering the 250 µg size.
品質
routinely evaluated by phosphorylation of 500μM JAK3tide (Catalog # 12-547)
ターゲットの説明
JAK3
物理的形状
Ni2+/NTA-agarose
保管および安定性
6 months at -70°C
その他情報
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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シグナルワード
Warning
危険有害性情報
危険有害性の分類
Skin Sens. 1
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Nature, 370(6485), 153-157 (1994-07-14)
Many cytokines function through interaction with receptors of the cytokine receptor superfamily. Although lacking catalytic domains, cytokine receptors couple ligand binding to induction of protein tyrosine phosphorylation. Recent studies have shown that one or more of the Janus kinase family
Nature, 370(6485), 151-153 (1994-07-14)
Interleukin-2 is an autocrine growth factor for T cells which also activates other cells including B cells and natural killer cells. The subunits of the interleukin-2 receptor (IL-2R) lack intrinsic enzymatic activity, but protein tyrosine phosphorylation is a critical event
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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