14-602-M

PI3 Kinase (p110α/p85α) Protein, active, 20 µg

Active complex of N-terminal His6-tagged recombinant full-length human p110α & untagged, recombinant, full length, human p85α. For use in Kinase Assays.

• 別名: Active PI3 Kinase Protein, PI3 Kinase p110α/p85α
• UNSPSCコード: 12352202
• eCl@ss: 32160405
• NACRES: NA.26

特性

• 由来生物: human
• 品質水準: 100
• リコンビナント: expressed in baculovirus infected Sf21 cells
• 分子量: M_w 125.3 kDa (p110α); M_w 83.7 kDa (p85α)
• メーカー／製品名: Upstate^®
• テクニック: activity assay: suitable (kinase)
• NCBIアクセッション番号: NM_006218.2
• UniProtアクセッション番号: P42336
• 遺伝子情報: human ... PIK3CA(5290)

詳細

詳細

Product Source: Coexpressed by baculovirus in Sf21 insect cells

Research area: Cell signaling

Protein Target: PI3Kα/p85α Target Sub-Family: PI3K/PI4K

Complex of N-terminal His6-tagged recombinant full-length human p110α and untagged, recombinant, full length, human p85α

アプリケーション

PI3 Kinase (p110α/p85α) Protein has been used in in vitro kinase assay.

生物化学的／生理学的作用

Phosphoinositide 3-kinases (PI3Ks) are enzymes that play a crucial role in cell signaling. They are responsible for activating signaling pathways that regulate important cellular processes such as cell survival, proliferation, protein synthesis, cell metabolism, cytoskeletal rearrangements, and vesicle trafficking. PI3Ks exhibits both lipid kinase activity (phosphorylation of inositol ring in phosphatidylinositol (PtdIns) lipids) and protein kinase activity (including autophosphorylation).

包装

Also available in 250μg size as catalog # 14-602M - Call for pricing and availability.

品質

routinely evaluated by PIProfiler

物理的形状

Ni²⁺/NTA-agarose

保管および安定性

6 months at -70°C

その他情報

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法的情報

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.