1.37037

グアニジン 塩酸塩

EMPROVE^® EXPERT, NF

• 別名: アミノホルムアミジン 塩酸塩, アミノメタンアミジン 塩酸塩, グアニジウムクロリド
• 化学式: NH₂C(=NH)NH₂ · HCl
• CAS番号: 50-01-1
• 分子量: 95.53
• Beilstein: 3591990
• MDL番号: MFCD00013026
• UNSPSCコード: 12352107
• EC Index Number: 200-002-3

特性

• 認証: NF
• 品質水準: 500
• 製品種目: EMPROVE^® EXPERT
• 有効性: 655.3-907.1 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• 特徴: RNase and DNase free
• pH: 4.5-5.5 (20 °C, 100 g/L in H₂O)
• mp: 180-185 °C (lit.); 188 °C
• 溶解性: 2150 g/L
• 密度: 1.3 g/cm³ (lit.)
• かさ密度: 550‑620 kg/m³
• 保管温度: 15-25°C
• SMILES記法: Cl[H].NC(N)=N
• InChI: 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H
• InChI Key: PJJJBBJSCAKJQF-UHFFFAOYSA-N

詳細

詳細

Finding the right chemical that matches your pharma and biopharma manufacturing needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for pharma and biopharma manufacturing withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Our SAFC^® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of downstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

アプリケーション

強いカオトロピック剤で、タンパク質の変性とその後のリフォールディングに有用です。この強い変性剤は、封入体などの不溶性タンパク質や変性タンパク質を可溶化できます。タンパク質または酵素を活性型にリフォールディングする際の最初のステップとして利用されます。尿素およびジチオスレイトール(DTT)が必要となる場合があります。

その他情報

Due to its low microbial and endotoxin limits, Guanidinium chloride Emprove^® Expert is suitable for biopharma manufacturing needs.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302 + H332 - H315 - H319
• 注意書き: P261 - P264 - P301 + P312 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable