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Merck

1.01728

Sigma-Aldrich

OSTEOSOFT®

mild decalcifier-solution for histology

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About This Item

UNSPSCコード:
12352401

品質水準

形状

liquid

dark red

pH

7.0-7.3 (20 °C in H2O)

密度

1.10 g/mL at 20 °C

アプリケーション

diagnostic assay manufacturing
hematology
histology

保管温度

15-25°C

詳細

This ready-to-use product, OSTEOSOFT® - mild decalcifier-solution for histology, has been specifically developed for human cell diagnostics in humans and is used for the demineralization and decalcification of bones, punched bone-marrow specimens, and other hard tissue of human origin.
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®(Product number 1.01736), can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and acetic acid. The amount of OSTEOSOFT®needed is dependent upon on the size, type and thickness of the material. Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. OSTEOSOFT® is used only once and fresh solution must be used for each tissue. The quantity of OSTEOSOFT® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

法的情報

OSTEOMOLL is a registered trademark of Merck KGaA, Darmstadt, Germany
OSTEOSOFT is a registered trademark of Merck KGaA, Darmstadt, Germany

ピクトグラム

CorrosionHealth hazard

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Eye Dam. 1 - STOT RE 2 Inhalation

ターゲットの組織

Respiratory Tract

保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

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Ivana Kurelac et al.
Journal of clinical medicine, 8(12) (2019-12-15)
A cogent issue in cancer research is how to account for the effects of tumor microenvironment (TME) on the response to therapy, warranting the need to adopt adequate in vitro and in vivo models. This is particularly relevant in the

関連コンテンツ

標準および特殊な染色法および色素を用いた、研究および臨床病理検査用の生物学的組織の染色の重要性についてご紹介します。

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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