07-1348

Anti-phospho-PLK1 (Ser137) Antibody

from rabbit, purified by affinity chromatography

• 別名: Polo-like kinase 1, Serine/threonine-protein kinase 13, cell cycle regulated protein kinase, polo (Drosophia)-like kinase, polo like kinase, polo-like kinase (Drosophila), polo-like kinase 1 (Drosophila)
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: human, mouse, rat
• 化学種の反応性（ホモロジーによる予測）: bovine
• テクニック: western blot: suitable
• NCBIアクセッション番号: NP_005021
• UniProtアクセッション番号: P53350
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: phosphorylation (pSer137)
• 遺伝子情報: human ... PLK1(5347)

詳細

詳細

Polo-like Kinase 1 (PLK1) is a serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Expressed PLK protein accumulates to a maximum during the G2 and M phases, declines to a nearly undetectable level following mitosis and throughout G1 phase, and then begins to accumulate again during S phase.

特異性

This antibody recognizes phosphorylated PLK1 at Ser137.

免疫原

KLH-conjugated linear peptide corresponding to human phosphoylated PLK1 at and around Ser137.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
キナーゼ及びホスファターゼ

Detect phospho-PLK1 (Ser137) using this Anti-phospho-PLK1 (Ser137) Antibody validated for use in WB.

Western Blot (SNAP ID) Analysis: 0.5 µg/mL of this antibody detected PLK1 phosphorylated at Ser137 in human placenta tissue lysate.

品質

Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected PLK1 phosphorylated at Ser137 in lambda phosphatase treated and untreated human placenta tissue lysate.

ターゲットの説明

68 kDa

物理的形状

Affinity purified

Affinity purified rabbit serum in 0.1M Tris-Glycine (pH7.4), 150mM NaCl with 0.05% sodium azide.

保管および安定性

Maintain refrigerated at 2-8°C for up to 12 months.

アナリシスノート

Control
Lambda phosphatase treated and untreated human placenta tissue lysate.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable