05-829-AF555

Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor^™ 555 Conjugate

clone DM1A, from mouse, ALEXA FLUOR^™ 555

• 別名: Tubulin alpha-1 chain, Alpha-tubulin, Alpha-1 tubulin
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: ALEXA FLUOR^™ 555
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: DM1A, monoclonal
• 化学種の反応性: guinea pig, gerbil, mouse, bovine, avian, human, rat, porcine
• テクニック: immunocytochemistry: suitable
• アイソタイプ: IgG1
• NCBIアクセッション番号: NP_001292201.1
• UniProtアクセッション番号: P02552
• ターゲットの翻訳後修飾: unmodified

詳細

詳細

Tubulin alpha-1 chain (UniProt P02552) is encoded by the TUBA1C (also known as TUBA1) gene (Gene ID 429035) in Gallus gallus (Chicken) species. Microtubules are cytoskeletal filaments composed of of alpha-/beta-tubulin heterodimers that self-assemble head-to-tail to form protofilaments and laterally to form a hollow tubes. Various post-translational modifications (PTMs), including acetylation, polyglutamylation, polyglycylation, detyrosination, phosphorylation, and palmitoylation, can regulate the polymerization properties of tubulins and/or their interactions with microtubule associated proteins (MAPs) and motor proteins.

特異性

Clone DM1A recognizes α-Tubulin, MW 50-60 kDa. The epitope recognized by this antibody has been mapped to the C-terminal 25 amino acids (AALEKDYEEVGVDSVEGEGEEEGEE).

免疫原

Epitope: C-terminal 25 amino acids.

Purified chicken brain α-tubulin.

アプリケーション

Research Category
細胞骨格

Research Sub Category
Cytoskeleton

The unconjugated antibody (Cat. No. 05-829) is shown to be suitable also for immunocytochemistry, immunofluorescence, and Western blotting applications.

This Anti-α-Tubulin Antibody, clone DM1A, Alexa Fluor^™ 555 Conjugate is validated for use in Immunocytochemistry for the detection of α-Tubulin.

品質

Evaluated by Immunocytochemistry in A431 cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected α-tubulin in A431 cells.

ターゲットの説明

~50 kDa observed.

物理的形状

Protein G purified.

Purified mouse monoclonal IgG1 antibody conjugate in PBS with 15 mg/mL BSA and 0.1 % sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

その他情報

Concentration: Please refer to lot specific datasheet.

法的情報

ALEXA FLUOR is a trademark of Life Technologies

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable