04-1584

Anti-Interleukin-2 (IL-2) Antibody, clone 3F9

clone AB12.38.35C3.3F9, from mouse

• 別名: interleukin 2, involved in regulation of T-cell clonal expansion, aldesleukin, T cell growth factor, lymphokine, Aldesleukin, interleukin-2, T-cell growth factor
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: AB12.38.35C3.3F9, monoclonal
• 化学種の反応性: human
• テクニック: western blot: suitable
• アイソタイプ: IgG2bκ
• NCBIアクセッション番号: NP_000577
• UniProtアクセッション番号: P60568
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... IL2(3558)

詳細

詳細

Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be interesting clinical targets for those diseases. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies.

免疫原

Full length recombinant protein corresponding to human IL-2.

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
サイトカイン及びサイトカイン受容体

Detect Interleukin-2 (IL-2) using this Anti-Interleukin-2 (IL-2) Antibody, clone 3F9 validated for use in WB.

品質

Evaluated by Western Blot in lysate from cells expressing human IL-2 recombinant protein.

Western Blot Analysis: 0.5 µg/mL of this antibody detected 10 µg of human IL-2 recombinant protein.

ターゲットの説明

~15 kDa observed

物理的形状

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Human IL-2 recombinant protein

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable