おすすめの製品
由来生物
chicken
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
交差性
rat, mouse, human
メーカー／製品名
Genway 15-288-22461F
テクニック
indirect ELISA: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... IL2(3558)
詳細
IL2 (interleukin 2) is a pro-inflammatory cytokine, which is predominantly synthesized by activated T-cells and dendritic cells (DCs). T-cells also act as effector of IL-2 as they contain the interleukin 2 receptor (IL2R). This gene is localized to human chromosome 4q27, and codes for a glycoprotein with a molecular weight of 14-17kDa.
アプリケーション
Anti-Interleukin-2 antibody produced in chicken is suitable for the production of anti-IL2 surface-conjugated microtoroids. It is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生物化学的／生理学的作用
Interleukin 2 (IL-2) is an interleukin and is a cytokine signaling molecule in the immune system. It plays an important role in signal transduction for biological functions of IL-2. Upregulation of IL-2 combined with activation of IL-2-dependent signaling pathways may contribute to the pathogenesis of Focal cortical dysplasia (FCD). Aerosol interleukin-2 (IL-2) increases the number of intravenously injected human natural killer (NK) cells in the lungs by stimulating local NK cell proliferation. The effect on NK cell proliferation is organ specific, which makes it ideal for the specific targeting of lung metastasis.
物理的形状
Solution in phosphate buffered saline containing 0.02% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
GW22461F-BULK:
GW22461F-VAR:
GW22461F-50UG:
最新バージョンのいずれかを選択してください：
Marta Fichna et al.
Molecular biology reports, 40(12), 6957-6963 (2013-10-25)
Polymorphic variants at the interleukin-2 (IL2) locus affect the risk of several autoimmune disorders. Our aim was to evaluate the association of the four IL2 polymorphisms (rs6822844, rs6534349, rs2069762 and rs3136534) with type 1 diabetes (T1D) in the Polish population
Jipseol Jeong et al.
Veterinary immunology and immunopathology, 162(3-4), 154-161 (2014-12-03)
Interleukin (IL)-2 and IL-15 receptor β (IL-2/15Rβ, CD122) play important roles in signal transduction for biological functions of IL-2 and IL-15. We found that ducks possess three different IL-2/15Rβ transcripts, a conventional form (duIL-2/15Rβ) and two variants. Comparisons between the
Marcel Joly et al.
Journal of theoretical biology, 335, 57-78 (2013-06-29)
In this paper, we sought to identify the CD4(+) T-cell dynamics in the course of HIV infection in response to continuous and intermittent intravenous courses of interleukin-2 (IL-2), the principal cytokine responsible for progression of CD4(+) T-lymphocytes from the G1
Wei Guo et al.
Journal of neuropathology and experimental neurology, 73(3), 206-222 (2014-02-04)
Focal cortical dysplasia (FCD) is a well-known cause of medically intractable epilepsy. To understand the potential role of the inflammatory cytokine interleukin 2 (IL-2) in the pathogenesis of FCD, we investigated the expression patterns of IL-2 and its receptors (IL-2Rs)
Agata Kosmaczewska
International journal of molecular sciences, 15(10), 18574-18592 (2014-10-17)
For many years, the role of interleukin-2 (IL-2) in autoimmune responses was established as a cytokine possessing strong pro-inflammatory activity. Studies of the past few years have changed our knowledge on IL-2 in autoimmune chronic inflammation, suggesting its protective role
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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