N-107

Norhydromorphone hydrochloride solution

1.0 mg/mL in methanol (as free base), certified reference material, ampule of 1 mL, Cerilliant^®

• 実験式（ヒル表記法）: C₁₆H₁₈ClNO₃
• CAS番号: 14140-35-3
• 分子量: 307.77
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol (as free base)
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C

詳細

詳細

A long-term urinary metabolite of hydromorphone, a very potent opioid analgesic marketed under brand names including Palladone and Dilaudid. Hydromorphone is often used medicinally as an alternative to morphine for treatment of pain or as a cough suppressant for painful coughing resulting from continued bronchial irritation. This certified reference standard is suitable for use as a starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis, clinical toxicology, and pain prescription monitoring to urine drug testing and pharmaceutical research.

アプリケーション

• Bifunctional opioid properties: Research on Norhydromorphone demonstrates its potential as a bifunctional opioid with intriguing effects due to substitutions in the N-Phenethyl moiety. This investigation into its unique properties can advance understanding of opioid receptor interactions, relevant to drug development and pain management strategies (Wang et al., 2020).
• Opioid metabolite detection: Norhydromorphone, identified as a significant opioid metabolite, is crucial for studies using exhaled breath condensate (EBC) techniques. This method, applicable in pharmaceutical research, aids in non-invasive monitoring and analyzing opioid consumption and metabolism (Borras et al., 2019).
• Capillary electrophoresis in metabolism studies: The use of capillary electrophoresis to study Norhydromorphone metabolism offers a precise analytical method, enhancing the biochemical assay capabilities in opioid pharmacology research (Baldacci and Thormann, 2006).
• Antinociceptive activities: Identification and synthesis of Norhydromorphone were followed by evaluation of its antinociceptive activities using the rat formalin test. This research contributes to understanding its potential as an opioid analgesic in pain management (Zheng, McErlane, and Ong, 2004).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup