LM2144

Sphingosine-1-Phosphate (d17:1)

Avanti Research^™ - A Croda Brand

• 別名: heptadeca-sphing-4-enine-1-phosphate
• 実験式（ヒル表記法）: C₁₇H₃₆NO₅P
• CAS番号: 474923-27-8
• 分子量: 365.45
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• フォーム: ethanol solution
• 包装: pkg of 1 × 1 mL (LM2144-1EA)
• メーカー／製品名: Avanti Research^™ - A Croda Brand
• 濃度: ~10 μg/mL (Refer to C of A for lot specific concentration.)
• アプリケーション: lipidomics; metabolomics
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O
• InChI: 1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1
• InChI Key: VITGNIYTXHNNNE-LHMZYYNSSA-N

詳細

詳細

Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals and is produced in endothelial cells. It is a cellular metabolite and signalling lipid in mammalian cells. S1P is synthesized by sphingosine kinases from sphingosine. It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).

生物化学的／生理学的作用

Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes. It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes. S1P regulates skin dendritic cells and keratinocytes

包装

2 mL Amber Glass Sealed Ampule (LM2144-1EA)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS02,GHS07
• シグナルワード: Danger
• 危険有害性情報: H225,H319
• 注意書き: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• 危険有害性の分類: Eye Irrit. 2 - Flam. Liq. 2
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 55.4 °F - closed cup
• 引火点(℃): 13.0 °C - closed cup