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形状
powder
包装
pkg of 1 × 25 mg (880343P-25mg)
メーカー／製品名
Avanti Research™ - A Croda Brand 880343P
脂質タイプ
phospholipids
cardiolipins
輸送温度
dry ice
保管温度
−20°C
SMILES記法
O=P([O-])(OCC[N+](C)(C)C)OC[C@H](OC(CCC(OC1CC[C@]2(C)C(C1)=CCC3C2CC[C@]4(C)C3CC[C@H]4[C@@H](C)CCCC(C)C)=O)=O)COC(CCCCCCCCCCCCCCC)=O
アプリケーション
PChemsPC or 1-palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine might be used to study its pharmacokinetics and biodistribution patterns in comparison with phospholipid-cholesterol liposomes. It might also be used as a component in the monolayer to study its characterization at the air/water interface.
生物化学的／生理学的作用
PChemsPC or 1-palmitoyl-2-cholesterylhemisuccinoyl-sn-glycero-3-phosphocholine is a sterol-phospholipid hybrid. Cholesterol incorporation with phospholipids reduces the permeability of the lipid bilayer, organizes phospholipid chains and avoids the phospholipid phase transition. This improves the stability of the vesicles.
包装
5 mL Amber Glass Screw Cap Vial (880343P-25mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
WGK
WGK 3
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
880343P-25MG:
880343P-BULK:
880343P-VAR:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Michał Flasiński et al.
Langmuir : the ACS journal of surfaces and colloids, 32(16), 4095-4102 (2016-04-06)
The two synthetic sterol-phospholipid hybrids DCholPC and PCholPC were investigated in monolayers at the air/water interface. Study was based on π-A isotherm analysis complemented with application of grazing incidence X-ray diffraction. It was found that both compounds are capable of
Zhaohua Huang et al.
Journal of the American Chemical Society, 130(46), 15702-15712 (2008-10-28)
We synthesized a family of sterol-modified glycerophospholipids (SML) in which the sn-1 or sn-2 position is covalently attached to cholesterol and the alternative position contains an aliphatic chain. The SML were used to explore how anchoring cholesterol to a phospholipid
Maryam Iman et al.
International journal of pharmaceutics, 408(1-2), 163-172 (2011-02-01)
1,2-Di-stigma-steryl-hemi-succinoyl-sn-glycero-3-phosphocholine (DSHemsPC) is a new lipid in which two molecules of stigmasterol (an inexpensive plant sterol) are covalently linked via a succinic acid to glycerophosphocholine. Since amphotericin B (AmB) interacts with sterols, we postulated that DSHemsPC could be used in
F Foglia et al.
Langmuir : the ACS journal of surfaces and colloids, 27(13), 8275-8281 (2011-06-04)
Langmuir isotherm, neutron reflectivity, and small angle neutron scattering studies have been conducted to characterize the monolayers and vesicular bilayers formed by a novel chimeric phospholipid, ChemPPC, that incorporates a cholesteryl moeity and a C-16 aliphatic chain, each covalently linked
Zhaohua Huang et al.
Angewandte Chemie (International ed. in English), 48(23), 4146-4149 (2009-05-09)
Extreme makeover of cholesterol: Cholesterol exchange is a major reason for the instability of liposomes in blood. The formation of a covalent hybrid between cholesterol and glycerophosphocholine preserves the bilayer-stabilizing effect of free cholesterol but prevents its transfer from the
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