860842P

18:0(2R-OH) Sulfo GalCer

Avanti Research^™ - A Croda Brand 860842P, powder

• 別名: 3-O-sulfo-D-galactosyl-β1-1′-N-[2"(R)-hydroxystearyl]-D-erythro-sphingosine (ammonium salt), (synthetic)
• 実験式（ヒル表記法）: C₄₂H₈₄N₂O₁₂S
• CAS番号: 2260670-26-4
• 分子量: 841.19
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 形状: powder
• 包装: pkg of 1 × 1 mg (860842P-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 860842P
• 脂質タイプ: sphingolipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC([C@H](O)CCCCCCCCCCCCCCCC)=O)CO[C@H](O1)[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H]([C@H]1CO)O.[NH4+]

詳細

詳細

18:0(2R-OH) Sulfo GalCer, also known as 3-O-sulfo-D-galactosyl-β1-1′-N-[2"(R)-hydroxystearyl]-D-erythro-sphingosine, is a sulfatide that belongs to the class of sphingolipids. It is highly found in membranous myelin sheath formed around nerve axons in gangliosides. This sulfated galactosylceramide contains 3-O-sulfo-β-d-galactose moiety linked to transmembrane-embedded unique ceramide containing 18C long chain base fatty acid (stearic acid) with 2′-hydroxyl group in R configuration.

生物化学的／生理学的作用

Sulfatides are involved in various cellular processes such as protein trafficking, signal transduction and neuronal cell differentiation. Accumulation of sulfoglycolipids (mainly sulfo-galactosylceramide, S-GalCer) in lysosomes, due to the inherited deficiency of arylsulfatase A (ASA), causes metachromatic leukodystrophy in humans. In mice, deficiency of sulfatide causes paralysis due to demyelination.

包装

5 mL Amber Glass Screw Cap Vial (860842P-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• 引火点(°F): No data available
• 引火点(℃): No data available