860526P

1-O-Acyl-Ceramide

Avanti Polar Lipids 860526P, powder

• 別名: 1-oleoyl-N-heptadecanoyl-D-erythro-sphingosine
• 実験式（ヒル表記法）: C₅₃H₁₀₁NO₄
• CAS番号: 1246303-19-4
• 分子量: 816.37
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• 形状: powder
• 包装: pkg of 1 × 5 mg (860526P-5mg)
• メーカー／製品名: Avanti Polar Lipids 860526P
• 脂質タイプ: sphingolipids
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

詳細

詳細

1-O-Acyl-Ceramide is an epidermal ceramide present in mouse and human epidermis. It comprises long chain fatty acids in 1-O-position and is synthesized in the endoplasmic reticulum-related sites.

アプリケーション

1-O-Acyl-Ceramide is suitable for use as a lipid standard in

• high performance thin layer chromatography (HPTLC)
• in mass and nuclear magnetic resonance spectroscopy for the quantification of lipids isolated from vernix caseosa skin cream
• in liquid chromatography-tandem mass spectrometry for the quantification of 1-O-Acyl ceramides from liver samples

生物化学的／生理学的作用

1-O-Acyl-Ceramide functions in maintaining water barrier homeostasis. Deficiency of the glucosylceramide synthase enzyme leads to the accumulation of O-acylceramides. Treatment of human monoclonal antibody, REMD 2.59 leads to the accumulation of 1-O-acyl-ceramides in soleus muscle and depletion in liver.

包装

5 mL Amber Glass Screw Cap Vial (860526P-5mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3