840858P

16:0-18:2 PA

1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt), powder

• 別名: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (sodium salt); PA(16:0/18:2(9Z,12Z))
• 実験式（ヒル表記法）: C₃₇H₆₈O₈PNa
• CAS番号: 322647-59-6
• 分子量: 694.89
• UNSPSCコード: 51191904
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• 形状: powder
• 包装: pkg of 1 × 100 mg (840858P-100mg); pkg of 1 × 25 mg (840858P-25mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 840858P
• 脂質タイプ: phospholipids; cardiolipins
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: [H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C37H69O8P.Na/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-37(39)45-35(34-44-46(40,41)42)33-43-36(38)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2;/h11,13,17-18,35H,3-10,12,14-16,19-34H2,1-2H3,(H2,40,41,42);/q;+1/p-1/b13-11-,18-17-;/t35-;/m1./s1
• InChI Key: IYNPOFCKGPJAFU-HQFKUYMNSA-M

詳細

詳細

Phosphatidic acid (PA) is an anionic, membrane structural lipid. It is amphipathic in nature containing a polar head group and two long hydrophobic acyl chains. PA acts as a parent compound for more complex membrane phospholipids. 16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate is a sodium salt of phosphatidic acid, with substitution of palmitic acid and linolenic acid at the sn-1 and sn-2 positions respectively, in the glycerol backbone.

アプリケーション

16:0-18:2 PA or 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt) might be used as a standard in thin-layer chromatography (TLC) for the separation of ginger and grapefruit exosome-like nanoparticles (ELN)-derived lipids. It might also be used in filter-blotting assay, to study the interaction of AT-hook motif-containing nuclear localized protein 4 (Ahl4) with PA.

生物化学的／生理学的作用

Phosphatidic acid (PA) is a bioactive lipid and acts as a secondary messenger. It is associated with hydrogen peroxide production in the neutrophils. PA stimulates the action of protein kinase for neutrophil respiratory burst. It also participates in Ras mediated signaling pathways. PA reacts with water and other phospholipids to produce lipid bilayers and multicomponent bilayers respectively.

包装

5 mL Clear Glass Sealed Ampule (840858P-100mg)

5 mL Clear Glass Sealed Ampule (840858P-25mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• 保管分類コード: 11 - Combustible Solids