810218C

C6-NBD Sphingomyelin

Avanti Research^™ - A Croda Brand 810218C

• 別名: N-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-sphingosine-1-phosphocholine
• 実験式（ヒル表記法）: C₃₅H₆₁N₆O₉P
• CAS番号: 94885-04-8
• 分子量: 740.87
• UNSPSCコード: 12352211
• NACRES: NA.25

特性

• アッセイ: >99% (TLC)
• フォーム: liquid
• 包装: pkg of 1 × 1 mL (810218C-1mg)
• メーカー／製品名: Avanti Research^™ - A Croda Brand 810218C
• 濃度: 1 mg/mL (810218C-1mg)
• 輸送温度: dry ice
• 保管温度: −20°C
• InChI: 1S/C35H61N6O9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-21-32(42)30(28-49-51(46,47)48-27-26-41(2,3)4)37-33(43)22-19-17-20-25-36-29-23-24-31(40(44)45)35-34(29)38-50-39-35/h18,21,23-24,30,32,42H,5-17,19-20,22,25-28H2,1-4H3,(H2-,36,37,39,43,46,47)/b21-18+/t30-,32+/m0/s1
• InChI Key: YDBDYTGWMRUUSN-PERJAUJZSA-N

詳細

詳細

C6-NBD Sphingomyelin is a fluorescent derivative of sphingomyelin. Its fluorescent property is due to presence of NBD (2-(4-nitro-2,1,3-benzoxadiazol-7-yl) aminoethyl) group. Sphingomyelin is generally concentrated in the outer leaflet of the plasma membrane.

アプリケーション

C6-NBD Sphingomyelin is suitable to study sphingomyelin endocytosis using fluorescence microscopy.

生物化学的／生理学的作用

Sphingomyelin (SM) is involved in signal transduction and membrane trafficking. It is synthesized by the transfer of phosphocholine from phosphatidylcholine onto ceramide, catalysed by sphingomyelin synthase on the cell surface and in lumen of the Golgi. SM has high packing density and affinity for sterol which offer a strong barrier to extracellular environment.

包装

5 mL Amber Glass Screw Cap Vial (810218C-1mg)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全性情報

• ピクトグラム: GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• 注意書き: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• 危険有害性の分類: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• ターゲットの組織: Central nervous system, Liver,Kidney
• WGK: WGK 3