おすすめの製品
![(3RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazin-7-one certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland](/deepweb/assets/sigmaaldrich/product/structures/277/860/e3312473-93c3-4ac2-bbb9-dfedf9b6ef2b/640/e3312473-93c3-4ac2-bbb9-dfedf9b6ef2b.png)
フォーム
powder
包装
pkg of 1 × 100 mg (141101P-100mg)
pkg of 5 × 100 mg (141101P-500mg)
メーカー／製品名
Avanti Research™ - A Croda Brand
脂質タイプ
lipid extracts
輸送温度
dry ice
保管温度
−20°C
関連するカテゴリー
詳細
Brain Extract Polar comprises phosphatidylethanolamine as a major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol.
Brain Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.
アプリケーション
Brain Extract Polar has been used in parallel artificial membrane permeability assay (PAMPA) for coating membrane to evaluate blood brain-barrier permeability, and for drug permeability studies.
生物化学的／生理学的作用
Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes. Brain lipid, especially the polar fraction play a key role in the inhibition of prion seeded amyloid formation.
包装
5 mL Clear Glass Sealed Ampule (141101P-100mg)
5 mL Clear Glass Sealed Ampule (141101P-500mg)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
保管分類コード
11 - Combustible Solids
WGK
WGK 3
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
141101P-BULK:
141101P-500MG:
141101P-100MG:
141101P-VAR:
最新バージョンのいずれかを選択してください：
この製品を見ている人はこちらもチェック
Clearance-dependent underprediction of in vivo intrinsic clearance from human hepatocytes: comparison with permeabilities from artificial membrane (PAMPA) assay, in silico and caco-2 assay, for 65 drugs
Hallifax D, et al.
European Journal of Pharmaceutical Sciences, 45(5), 570-574 (2012)
Rapid screening of brain-penetrable antioxidants from natural products by blood-brain barrier specific permeability assay combined with DPPH recognition
Zhu J, et al.
Journal of Pharmaceutical and Biomedical Analysis, 151, 42-48 (2018)
Estefanía de Munck et al.
PloS one, 11(9), e0162723-e0162723 (2016-09-16)
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron degenerative disease that has no effective treatment up to date. Drug discovery tasks have been hampered due to the lack of knowledge in its molecular etiology together with the limited animal
David S Wexler et al.
Journal of biomolecular screening, 10(4), 383-390 (2005-06-21)
Solubility and permeability are intimately linked in drug absorption processes. They have, however, been traditionally assayed separately. To support this linkage, a combined solubility/permeability assay was developed for determining absorption properties of chemical entities. First, solubility is determined at 4
Endogenous brain lipids inhibit prion amyloid formation in vitro
Hoover CE, et al.
Journal of Virology, 91(9), e02162-e02116 (2017)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
製品に関するお問い合わせはこちら（テクニカルサービス）