QBD10819

MAL-dPEG^®₁₁-Lipoamide

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₃₉H₆₉N₃O₁₅S₂
• CAS番号: 1334172-73-4
• 分子量: 884.11
• MDL番号: MFCD21363248
• UNSPSCコード: 51171641
• PubChem Substance ID: 329823959
• NACRES: NA.22

特性

• アッセイ: >90%
• フォーム: solid or viscous liquid
• 反応適合性: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: gold reactive
• ポリマー構造: shape: linear; functionality: heterobifunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: O=C(CCCCC1SSCC1)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
• InChI: 1S/C39H69N3O15S2/c43-36(4-2-1-3-35-8-34-58-59-35)40-9-12-47-14-16-49-18-20-51-22-24-53-26-28-55-30-32-57-33-31-56-29-27-54-25-23-52-21-19-50-17-15-48-13-10-41-37(44)7-11-42-38(45)5-6-39(42)46/h5-6,35H,1-4,7-34H2,(H,40,43)(H,41,44)
• InChI Key: MCLHFRMIEQEYEN-UHFFFAOYSA-N

詳細

特徴および利点

MAL-dPEG^®₁₁-lipoamide is a crosslinker designed to allow crosslinking of a sulfhydryl-containing molecule with a metal surface such as gold or silver. The hydrophilic, non-immunogenic, single molecular weight dPEG^® spacer is 59.3 Å long, providing good separation between the target molecule and the metal surface. The spacer also increases the hydrodynamic volume of the conjugate and improves its water solubility. The maleimide function forms a thioether bond with a sulfhydryl group. One possible application of this product is immobilization of an antibody or antibody fragment onto a metal surface. Peptides and small molecules with free sulfhydryl groups could also be used in this way.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable