QBD10631

Bis-MAL-Lysine-dPEG^®₄-TFP ester

• 別名: Polyethylene glycol
• 実験式（ヒル表記法）: C₃₇H₄₅F₄N₅O₁₃
• 分子量: 843.77
• MDL番号: MFCD28385461
• UNSPSCコード: 12352108
• PubChem Substance ID: 329823944
• NACRES: NA.22

特性

• アッセイ: >90%
• 形状: solid or viscous liquid
• 反応適合性: reagent type: cross-linking reagent; reactivity: thiol reactive
• ポリマー構造: shape: linear; functionality: monofunctional
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: O=C(C(NC(CCN1C(C=CC1=O)=O)=O)CCCCNC(CCN2C(C=CC2=O)=O)=O)NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

詳細

特徴および利点

Bis-MAL-Lysine-dPEG^®₄-TFP ester is a unique crosslinker containing two maleimide groups, one on each amine of lysine, a 4-unit, single molecular weight dPEG^® spacer arm, and a 2,3,5,6-tetrafluorophenyl (TFP) ester. Each maleimide group reacts with a sulfhydryl group, and the TFP ester reacts with a free amine. The single molecular weight dPEG^® spacer is hydrophilic and non-immunogenic. This reagent can be used to modify or form conjugates with antibodies, antibody fragments, peptides, and small molecules.

法的情報

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable