934372

MC-Val-Cit-PAB-PNP

≥95%

• 別名: L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N⁵-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
• 実験式（ヒル表記法）: C₃₅H₄₃N₇O₁₁
• CAS番号: 159857-81-5
• 分子量: 737.76
• Beilstein: 10322169
• MDL番号: MFCD22200431
• UNSPSCコード: 12352200
• PubChem Substance ID: 468592337

特性

• 品質水準: 100
• アッセイ: ≥95%
• 形状: powder
• 保管温度: 2-8°C

詳細

アプリケーション

This is a bifunctional cathepsin cleavable linker used in the construction of antibody drug conjugates (ADC).

特徴および利点

The maleimide functionality can be used for bioconjugation to thiols in monoclonal antibodies while the activated carbonate esters can be used for construction of carbamate linkages with amine containing payloads.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable