536822

PAMAM-OH dendrimer, generation 6 solution

5 wt. % in methanol

• 化学式: [NH₂(CH₂)₂NH₂]:(G=6);dendri PAMAM(NHCH₂CH₂OH)₂₅₆
• 分子量: 58298.21
• MDL番号: MFCD00197936
• UNSPSCコード: 12162002
• NACRES: NA.25

特性

• 詳細: amidoethanol surface groups
• 品質水準: 100
• フォーム: liquid
• 分子量: generation 6
• 特徴: core type ethylenediamine core (2-carbon core)
• 濃度: 5 wt. % in methanol
• 表面基数: 256
• 屈折率: n20/D 1.336
• 密度: 0.807 g/mL at 25 °C
• 保管温度: 2-8°C

詳細

詳細

PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality.

アプリケーション

PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers.

物理的形状

表面(末端)に256個の水酸基が存在します。

法的情報

Manufactured by Dendritech^®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 3
• 引火点(°F): 51.8 °F - closed cup
• 引火点(℃): 11 °C - closed cup