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品質水準
アッセイ
99%
形状
solid
bp
113 °C/700 mmHg (lit.)
mp
36-41 °C (lit.)
官能基
amide
SMILES記法
O=CNC1CCCCC1
InChI
1S/C7H13NO/c9-6-8-7-4-2-1-3-5-7/h6-7H,1-5H2,(H,8,9)
InChI Key
SWGXDLRCJNEEGZ-UHFFFAOYSA-N
遺伝子情報
human ... ADH1A(124) , ADH1B(125) , ADH1C(126) , ADH4(127) , ADH7(131) , EPHX2(2053)
mouse ... Ephx2(13850)
詳細
N-Cyclohexylformamide binds to the complex of horse liver alcohol dehydrogenase with NADH and is similar to the Michaelis complex for aldehyde reduction catalyzed by the enzyme. It is formed during hydration of cyclohexyl isocyanide catalyzed by a novel enzyme isonitrile hydratase from Pseudomonas putida N19-2 .
アプリケーション
N-Cyclohexylformamide was used in the synthesis of 2-methylidene-1,3-selenazolidine derivatives.
シグナルワード
Danger
危険有害性情報
危険有害性の分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
ターゲットの組織
Respiratory system
保管分類コード
11 - Combustible Solids
WGK
WGK 2
引火点(°F)
>235.4 °F - closed cup
引火点(℃)
> 113 °C - closed cup
個人用保護具 (PPE)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
120685-BULK:
120685-VAR:
120685-25G:
120685-100G:
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Selenium-containing heterocycles from isoselenocyanates: synthesis of 2-methylidene-1, 3-selenazolidine derivatives.
Tetrahedron, 62(14), 3344-3354 (2006)
Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage.
The Journal of biological chemistry, 276(26), 23480-23485 (2001-04-18)
Isonitrile containing an N triple bond C triple bond was degraded by microorganism sp. N19-2, which was isolated from soil through a 2-month acclimatization culture in the presence of this compound. The isonitrile-degrading microorganism was identified as Pseudomonas putida. The
Biochemistry, 37(40), 14267-14278 (1998-10-07)
The binding of N-cyclohexylformamide (CXF) to the complex of horse liver alcohol dehydrogenase with NADH mimics that of the Michaelis complex for aldehyde reduction catalyzed by the enzyme. The Raman spectra of bound CXF and its 13C- and 15N-substituted derivatives
Uncompetitive inhibitors of alcohol dehydrogenases.
Advances in experimental medicine and biology, 463, 295-303 (1999-06-03)
Journal of molecular biology, 302(2), 441-453 (2000-09-06)
The structure of mouse class II alcohol dehydrogenase (ADH2) has been determined in a binary complex with the coenzyme NADH and in a ternary complex with both NADH and the inhibitor N-cyclohexylformamide to 2.2 A and 2.1 A resolution, respectively.
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