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Documenti fondamentali

T1283

Sigma-Aldrich

holo-Transferrin bovine

Iron-saturated, BioReagent, suitable for cell culture

Sinonimo/i:

Siderophilin, Siderophilin, iron-saturated

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About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.75

Livello qualitativo

Nome Commerciale

BioReagent

Saggio

97-100% (agarose gel electrophoresis)

Stato

powder

Concentrazione

~25 mM

tecniche

cell culture | mammalian: suitable

Impurezze

endotoxin, tested

Solubilità

H2O: 50 mg/mL

N° accesso UniProt

Condizioni di spedizione

ambient

Temperatura di conservazione

2-8°C

Informazioni sul gene

bovine ... TF(280705)

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Applicazioni

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Bovine holo-transferrin can be used with a wide range of cells types. Bovine holo-transferrin is loaded with iron prior to use and can be added directly to iron poor or iron-free cell culture media.

Risultati analitici

Purity by agarose gel electrophoresis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Animal science journal = Nihon chikusan Gakkaiho, 87(1), 84-91 (2015-10-16)
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Transplanting vascular endothelial cells (ECs) to support metabolism and express regenerative paracrine factors is a strategy to treat vasculopathies and to promote tissue regeneration. However, transplantation strategies have been challenging to develop, because ECs are difficult to culture and little
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The British journal of nutrition, 123(5), 489-498 (2019-11-13)
Despite the well-characterised mechanisms of amino acids (AA) regulation of milk protein synthesis in mammary glands (MG), the underlying specific AA regulatory machinery in bovine MG remains further elucidated. As methionine (Met) is one of the most important essential and
Guihua Du et al.
Development (Cambridge, England), 147(8) (2020-03-20)
Continual spermatogenesis relies on the actions of an undifferentiated spermatogonial population that is composed of stem cells and progenitors. Here, using mouse models, we explored the role of RNA-binding proteins (RBPs) in regulation of the biological activities of this population.
Francis Biville et al.
PloS one, 9(10), e107612-e107612 (2014-10-08)
The ability to acquire iron from various sources has been demonstrated to be a major determinant in the pathogenesis of Neisseria meningitidis. Outside the cells, iron is bound to transferrin in serum, or to lactoferrin in mucosal secretions. Meningococci can

Articoli

How transferrin and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies. The page introduces the in vitro chemistry and biochemistry of transferrin.

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