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SML0032

Sigma-Aldrich

Triacetyl resveratrol

≥98% (HPLC)

Sinonimo/i:

3,5,4′-Tri-O-acetylresveratrol, 5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate

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About This Item

Formula empirica (notazione di Hill):
C20H18O6
Numero CAS:
42206-94-0
Peso molecolare:
354.35
Numero MDL:
MFCD01546481
Codice UNSPSC:
12352200
ID PubChem:
329825102
NACRES:
NA.25

Saggio

≥98% (HPLC)

Forma fisica

powder

Condizioni di stoccaggio

protect from light

Colore

white to tan

Solubilità

DMSO: ≥18 mg/mL

applicazioni

metabolomics
vitamins, nutraceuticals, and natural products

Temperatura di conservazione

room temp

Stringa SMILE

CC(=O)Oc1ccc(cc1)\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2

InChI

1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+
PDAYUJSOJIMKIS-SNAWJCMRSA-N

Descrizione generale

Resveratrol (RSV) is a natural polyphenolic antioxidant.

Azioni biochim/fisiol

Resveratrol prodrug. SIRT inhibitor
Resveratrol (RSV) plays a protective role on the nervous and cardiovascular systems. It is considered as a modulator of energetic metabolism as it controls glucose homeostasis in obese mice, improves fatty acid oxidation (FAO) and promotes the expression of genes that participate in mitochondrial biogenesis.
Triacetyl resveratrol displays superior bioavailability to the parent compound, resveratrol. The compound induces p53 activity and inhibits proliferation in breast and prostate tumor cell lines.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Certificati d'analisi (COA)

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Resveratrol induces a mitochondrial complex I dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
Desquiret-Dumas V, et al.
The Journal of Biological Chemistry, 2013 (2013)
Tammy R Dugas et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(3), 646-651 (2018-08-10)
Peripheral artery disease is a cardiovascular disease characterized by a narrowing of arteries that supply blood to the extremities, particularly, the legs. When surgical intervention is warranted, the primary approach is balloon angioplasty. Drug coated balloons (DCB) designed to release
Xiaoyun Zeng et al.
Journal of agricultural and food chemistry, 65(22), 4384-4394 (2017-05-05)
The persistence of latent HIV reservoirs presents a significant challenge to viral eradication. Effective latency reversing agents (LRAs) based on "shock and kill" strategy are urgently needed. The natural phytoalexin resveratrol has been demonstrated to enhance HIV gene expression, although
Hyeanjeong Jeong et al.
International journal of molecular sciences, 20(17) (2019-09-05)
Epigenetic remodeling via histone acetylation has become a popular therapeutic strategy to treat Alzheimer's disease (AD). In particular, histone deacetylase (HDAC) inhibitors including M344 and SAHA have been elucidated to be new drug candidates for AD, improving cognitive abilities impaired
Yoojin Lee et al.
Journal of innate immunity, 13(2), 94-106 (2020-09-17)
Natural killer (NK) cells are innate immune lymphocytes that play an important role in anti-viral and anti-tumour immune responses. Several cancer immunotherapy approaches targeting NK cells are currently in clinical or preclinical development. Here, we aimed to find food nutrients
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