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Key Documents

34092

Supelco

Resveratrolo

analytical standard

Sinonimo/i:

3,4′,5-triidrossi-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol

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About This Item

Formula empirica (notazione di Hill):
C14H12O3
Numero CAS:
Peso molecolare:
228.24
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
LUKBXSAWLPMMSZ-OWOJBTEDSA-N

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Descrizione generale

Resveratrol, a non-flavonoid polyphenolic compound, is widely found in the skin of red grapes, nuts, berries, Polygonum cuspidatum root, etc. It is reportedly known to exhibit pharmacological properties including anti-cancer, anti-inflammatory, antioxidant, neuroprotectant, anti-atherogenic property and reduces the synthesis of pro-atherosclerotic substances.

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Resveratrol has been used as a phenolic analytical standard to determine its content in oat flour tarhana and different varieties of chicory using high-performance liquid chromatography with diode array detection (HPLC-DAD). It has also been used as an analytical standard to investigate its effectiveness in modulating several signaling pathways that are involved in carcinogenesis, via determining its anti-tumor potential in colorectal cancer as a proapoptotic agent in colorectal cancer cell lines, including HCT116, CO115 and SW48.
Inibitore selettivo della COX−1.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

>392.0 °F - closed cup - (External MSDS)

Punto d’infiammabilità (°C)

> 200.0 °C - closed cup - (External MSDS)

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Certificati d'analisi (COA)

Lot/Batch Number

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Sigma-Aldrich

567860

SRT1720

trans-Piceatannol phyproof® Reference Substance

PHL83891

trans-Piceatannol

BRD3308 ≥98% (HPLC)

Sigma-Aldrich

SML1639

BRD3308

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ε-Viniferin

Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells
Lu R and Serrero G
Journal of Cellular Physiology, 179, 297-304 (1999)
The impact of drying techniques on phenolic compound, total phenolic content and antioxidant capacity of oat flour tarhana
Degirmencioglu N, et al.
Food Chemistry, 194, 587-594 (2016)
Biological effects of resveratrol
Fremont L
Life Sciences, 66, 663-673 (2000)
Philippe de Medina et al.
Journal of medicinal chemistry, 48(1), 287-291 (2005-01-07)
We developed new stilbene derivatives of resveratrol (E)-1-(4'-hydroxyphenyl)-2-(3,5-dihydroxyphenyl)ethene) selective for AhR and devoid of affinity for ER. Among the 24 stilbenes synthesized, all display a higher affinity than resveratrol for AhR. (E)-1-(4'-Trifluoromethylphenyl)-2-(3,5-ditrifluoromethylphenyl)ethene (4e), (E)-1-(4'-methoxyphenyl)-2-(3,5-dichlorophenyl)ethene (4j), and (E)-1-(4'-chlorophenyl)-2-(3,5-dichlorophenyl)ethene (4b) are selective
W Zhang et al.
European journal of medicinal chemistry, 42(6), 841-850 (2007-02-24)
Agents that induce the activity of phase II enzymes play an important role in intervening with the carcinogenic process at the initiation stage. Resveratrol is well known for its chemopreventive activity against major stages of carcinogenesis. In this study, several

Articoli

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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