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C1017

Sigma-Aldrich

Citrinin

from Penicillium citrinum, ≥98% (HPLC), powder, mycotoxin

Sinonimo/i:

(3R,4S)-8-Hydroxy-3,4,5-Trimethyl-6-Oxo-4,6-Dihydro-3H-Isochromene-7-Carboxylic Acid, 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid

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About This Item

Formula empirica (notazione di Hill):
C13H14O5
Numero CAS:
518-75-2
Peso molecolare:
250.25
Beilstein:
5282243
Numero CE:
208-257-2
Numero MDL:
MFCD00006912
Codice UNSPSC:
12352200
ID PubChem:
24892302
NACRES:
NA.77

Nome del prodotto

Citrinin, from Penicillium citrinum, ≥98% (HPLC)

Origine biologica

Penicillium citrinum

Livello qualitativo

200

Saggio

≥98% (HPLC)

Stato

powder

Temperatura di conservazione

2-8°C

Stringa SMILE

C[C@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@@H]1C

InChI

1S/C13H14O5/c1-5-7(3)18-4-8-9(5)6(2)11(14)10(12(8)15)13(16)17/h4-5,7,15H,1-3H3,(H,16,17)/t5-,7-/m1/s1
CQIUKKVOEOPUDV-IYSWYEEDSA-N

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Categorie correlate

Descrizione generale

Citrinin is a mycotoxin from Penicillium citrinin that comprises a quinone methide component.

Applicazioni

Citrinin has been used as:
  • a standard for calibration curve preparation for citrinin quantification Monascus purpureus ATCC 36928
  • an internal standard in thin layer chromatography (TLC) for characterizing the citrinin from Aspergillus and Penicillium strains
  • standard to characterize citrinin for rotten apples TLC

Azioni biochim/fisiol

Citrinin is a predominant contaminant in agriculture supplies and food. It exhibits genotoxic, embryotoxic, and teratogenic properties. It is hepatonephrotoxin and a potent mycotoxin in rice grains.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301 + H311 + H331,H351

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
089M4111V
14190408
039M4033V
118M4076V
108M4104V

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M R Bragulat et al.
Letters in applied microbiology, 47(4), 286-289 (2009-02-26)
To assess the ability of fungi isolated from grapes to produce patulin and citrinin. A total of 446 Aspergillus isolates belonging to 20 species and 101 Penicillium isolates were inoculated in Czapek yeast extract agar and yeast extract sucrose agar
Effect of dissolved oxygen concentration on red pigment and citrinin production by Monascus purpureus ATCC 36928
Brazilian Journal of Chemical Engineering, 25, 247-253 (2008)
Li-Chuan Hsu et al.
Journal of agricultural and food chemistry, 60(32), 7880-7885 (2012-07-28)
Monascus species have traditionally been used in Asian food, with rice as their fermentation substrate. Red mold rice (RMR) contains citrinin, a nephrotoxic agent capable of exerting oxidative stress and cellular apoptosis. We investigated the components in RMR that could
Maja Segvić Klarić et al.
Archives of toxicology, 86(1), 97-107 (2011-07-09)
The aim of this study was to establish the involvement of calcium signalling in genotoxicity, apoptosis and necrosis evoked by ochratoxin A (OTA) and citrinin (CTN) alone or in combination in porcine kidney PK15 cells. Cell proliferation test (MTT) and
Vanesa Gimena Lourdes Zachetti et al.
Bioelectrochemistry (Amsterdam, Netherlands), 91, 37-43 (2013-02-19)
An amperometric biosensor based on horseradish peroxidase (EC1.11.1.7,H2O2-oxide-reductases) to determine the content of citrinin mycotoxin in rice samples is proposed by the first time. The method uses carbon paste electrodes filled up with multi-walled carbon nanotubes embedded in a mineral
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