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P1639

Sigma-Aldrich

Patulin

≥98.0% (HPLC)

Sinonimo/i:

Clavacin, Clavatin, Expansine, Gigantin, Leucopin, Mycoine C3, Terinin, 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one

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About This Item

Formula empirica (notazione di Hill):
C7H6O4
Numero CAS:
149-29-1
Peso molecolare:
154.12
Beilstein:
149675
Numero CE:
205-735-2
Numero MDL:
MFCD00005858
Codice UNSPSC:
51102829
ID PubChem:
24898227
NACRES:
NA.85

Livello qualitativo

300

Saggio

≥98.0% (HPLC)

Forma fisica

powder

Solubilità

water: 9-11 mg/mL

Spettro attività antibiotica

fungi

Modalità d’azione

cell membrane | interferes

Temperatura di conservazione

−20°C

Stringa SMILE

OC1OCC=C2OC(=O)C=C12

InChI

1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
ZRWPUFFVAOMMNM-UHFFFAOYSA-N

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Descrizione generale

Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

Applicazioni

Patulin has been used:
  • to study patulin contamination of bottled wine
  • in DNA-damaging activity of patulin in Escherichia coli
  • in molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus

Azioni biochim/fisiol

Mycotoxin with anti-bacterial, potassium uptake inhibitory, and possibly carcinogenic activities. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na+-K+ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

Altre note

Keep container tightly closed in a dry and well-ventilated place.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H300,H315

Classi di pericolo

Acute Tox. 2 Oral - Skin Irrit. 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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