217565

Barium chloride dihydrate

ACS reagent, ≥99%

• Formula empirica (notazione di Hill): BaCl₂ · 2H₂O
• Numero CAS: 10326-27-9
• Peso molecolare: 244.26
• Numero CE: 233-788-1
• Numero MDL: MFCD00149154
• Codice UNSPSC: 12352300
• ID PubChem: 329752201
• NACRES: NB.24

Proprietà

• Grado: ACS reagent
• Livello qualitativo: 200
• Saggio: ≥99%
• Forma fisica: powder, crystals or chunks
• Impurezze: ≤0.005% insolubles; ≤0.005% oxidizers
• Perdita: 14.0-16.0% loss on drying
• pH: 5.2-8.2 (25 °C, 5%)
• Cationi in tracce: Ca: ≤0.05%; Fe: ≤2 ppm; K: ≤0.0025%; Na: ≤0.005%; Sr: ≤0.1%; heavy metals: ≤5 ppm (by ICP-OES)
• Stringa SMILE: O.O.Cl[Ba]Cl
• InChI: 1S/Ba.2ClH.2H2O/h;2*1H;2*1H2/q+2;;;;/p-2; PWHCIQQGOQTFAE-UHFFFAOYSA-L

Descrizione

Applicazioni

Barium chloride dihydrate has been used:

• in patch-clamp electrophysiological studies to block subthreshold-activated potassium channels
• as an inward rectifier potassium (Kir) channel blocker to study the role of the channel by measuring the microglial membrane currents in response to voltage ramp stimuli after ATP injection
• to prepare the stock solution to make artificial cerebrospinal fluid (aCSF)

Azioni biochim/fisiol

Barium chloride is a potassium ion channel blocker. It is considered toxic. Barium chloride prevents the D2-like receptor-mediated hyperpolarisation of spinal central pattern generator (CPG) neurons

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301 - H319 - H332
• Consigli di prudenza: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2
• Codice della classe di stoccaggio: 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable