PHR1106
L-arginina
Pharmaceutical Secondary Standard; Certified Reference Material
Sinonimo/i:
Acido (S)-2-ammino-5-guanidinopentanoico
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About This Item
Formula condensata:
H2NC(=NH)NH(CH2)3CH(NH2)CO2H
Numero CAS:
Peso molecolare:
174.20
Beilstein:
1725413
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.24
Prodotti consigliati
Grado
certified reference material
pharmaceutical secondary standard
Livello qualitativo
agenzia
traceable to Ph. Eur. A1270000
traceable to USP 1042500
Famiglia di API
arginine
CdA
current certificate can be downloaded
tecniche
HPLC: suitable
gas chromatography (GC): suitable
Punto di fusione
222 °C (dec.) (lit.)
applicazioni
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
Formato
neat
Temperatura di conservazione
2-30°C
Stringa SMILE
N[C@@H](CCCNC(N)=N)C(O)=O
InChI
1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
ODKSFYDXXFIFQN-BYPYZUCNSA-N
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Descrizione generale
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. L-Arginine is a dibasic, semi-essential amino acid. It acts as a precursor for creatinine and is a natural constituent of most of the dietary proteins. It also plays a key role in many physiological processes such as tissue repair and reproduction.
Applicazioni
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Azioni biochim/fisiol
Substrato della sintasi del monossido di azoto, che viene convertita a citrullina e monossido di azoto (NO). Induce il rilascio di insulina con un meccanismo dipendente dal monossido di azoto.
Risultati analitici
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Altre note
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Nota a piè di pagina
To see an example of a Certificate of Analysis for this material enter LRAA7157 in the slot below. This is an example certificate only and may not be the lot that you receive.
Prodotti consigliati
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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Diane N Singhroy et al.
Retrovirology, 10, 73-73 (2013-07-23)
Protein arginine methyltransferase 6 (PRMT6) is a nuclear enzyme that methylates arginine residues on histones and transcription factors. In addition, PRMT6 inhibits HIV-1 replication in cell culture by directly methylating and interfering with the functions of several HIV-1 proteins, i.e.
Palaniraja Thandapani et al.
Molecular cell, 50(5), 613-623 (2013-06-12)
Motifs rich in arginines and glycines were recognized several decades ago to play functional roles and were termed glycine-arginine-rich (GAR) domains and/or RGG boxes. We review here the evolving functions of the RGG box along with several sequence variations that
Ahmed Moursy et al.
Nucleic acids research, 42(10), 6659-6672 (2014-04-03)
Regulation of SMN2 exon 7 splicing is crucial for the production of active SMN protein and the survival of Spinal Muscular Atrophy (SMA) patients. One of the most efficient activators of exon 7 inclusion is hnRNP G, which is recruited
John Pernow et al.
Cardiovascular research, 98(3), 334-343 (2013-02-19)
Functional integrity of the vascular endothelium is of fundamental importance for normal vascular function. A key factor regulating endothelial function is the bioavailability of nitric oxide (NO). Recently, the enzyme arginase has emerged as an important regulator of NO production
Hartmut Grasemann et al.
Current pharmaceutical design, 18(5), 726-736 (2012-01-11)
The concentrations of nitric oxide are decreased in airways of patients with cystic fibrosis. The reasons for this nitric oxide deficiency are incompletely understood but may include reduced production from nitric oxide synthases due to decreased expression, the enzymes in
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