158534

Trifluoromethanesulfonic acid

reagent grade, 98%

• Sinonimo/i: TFMSA, Triflic acid
• Formula condensata: CF₃SO₃H
• Numero CAS: 1493-13-6
• Peso molecolare: 150.08
• Beilstein: 1812100
• Numero CE: 216-087-5
• Numero MDL: MFCD00007514
• Codice UNSPSC: 12352100
• ID PubChem: 24849764
• NACRES: NA.21

Proprietà

• Grado: reagent grade
• Livello qualitativo: 200
• Densità del vapore: 5.2 (vs air)
• Tensione di vapore: 8 mmHg ( 25 °C)
• Saggio: 98%
• Forma fisica: liquid
• Indice di rifrazione: n20/D 1.327 (lit.)
• P. eboll.: 162 °C (lit.)
• Densità: 1.696 g/mL at 25 °C (lit.)
• Gruppo funzionale: fluoro; triflate
• Stringa SMILE: OS(=O)(=O)C(F)(F)F
• InChI: 1S/CHF3O3S/c2-1(3,4)8(5,6)7/h(H,5,6,7); ITMCEJHCFYSIIV-UHFFFAOYSA-N

Descrizione

Descrizione generale

Trifluoromethanesulfonic acid is the strongest monoprotic organic acid. It has been synthesized by the oxidation of bis(trifluoromethylthio)mercury with aqueous hydrogen peroxide. It undergoes complete dissociation in basic solvents such as dimethyl sulfoxide, dimethylacetamide and dimethylformamide. Its dissociation in non-aqueous solvents has been studied by conductometry. On mixing trifluoromethanesulfonic acid with HNO_3, it forms nitronium trifluoromethane sulfonate, which is an excellent nitrating reagent.

Applicazioni

Trifluoromethanesulfonic acid is a versatile reagent, employed as catalyst for the following studies:

• Friedel-Crafts acylation of aromatic compounds with methyl benzoate.
• Addition reaction of dialkyl disulfides to terminal alkynes.
• Synthesis of a single cyclic tetrasiloxane containing propylammonium trifluoromethanesulfonate and methyl side-chain groups (Am-CyTS).
• Preparation of starting reagents for the synthesis of fluorinated 2,5-substituted 1-ethyl-1H-benzimidazole derivatives.
• Synthesis of aryl triflates, the lactonization of alkenoic acids, and the formation of E-alkenes.

Trifluoromethanesulfonic acid may be used as an initiator for the cationic polymerization of styrene, hexamethylcyclotrisiloxane and L,L-dilactide.

Deglycosylation agent

Informazioni sulla sicurezza

• Pittogrammi: GHS05,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H290,H302,H314,H335
• Consigli di prudenza: P234 - P261 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Met. Corr. 1 - Skin Corr. 1B - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 8A - Combustible corrosive hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): >332.1 °F - Pensky-Martens closed cup
• Punto d’infiammabilità (°C): > 166.7 °C - Pensky-Martens closed cup
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter