5.00299

Nicotinamide

EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC

• Sinonimo/i: Nicotinamide, Nicotinamide, Niacinamide, 3-Pyridinecarboxamide
• Formula empirica (notazione di Hill): C₆H₆N₂O
• Numero CAS: 98-92-0
• Peso molecolare: 122.12
• Numero MDL: MFCD00006395
• Codice UNSPSC: 12352111
• Numero indice EU: 202-713-4

Proprietà

• agenzia: BP; JP; Ph. Eur.; USP
• Livello qualitativo: 500
• Conformità normativa: FCC
• Descrizione: EMPROVE^® ESSENTIAL Ph Eur,BP,USP,JP,FCC
• Nome Commerciale: EMPROVE^® ESSENTIAL
• Forma fisica: solid
• Temp. autoaccensione: 480 °C
• Potenza: 3530-3540 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rabbit)
• tecniche: API processing | cocrystal formation: suitable
• pH: 6.0-7.5 (20 °C, 50 g/L in H₂O)
• P. eboll.: 150-160 °C/0.0007 hPa
• Punto di fusione: 128-131 °C (sublimed)
• Temp. transizione: flash point 182 °C
• Densità: 1.40 g/cm³ at 20 °C
• applicazioni: liquid formulation; pharmaceutical; solid formulation
• Temperatura di conservazione: 15-25°C
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9); DFPAKSUCGFBDDF-UHFFFAOYSA-N

Descrizione

Descrizione generale

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Nicotinamide is a commonly used ingredient in food and pharmaceutical applications. In pharmaceutical formulations, nicotinamide has been used for a range of different dosage forms.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H319
• Consigli di prudenza: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classi di pericolo: Eye Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 302.0 °F - closed cup
• Punto d’infiammabilità (°C): 150 °C - closed cup