N3501

β-Nicotinamide mononucleotide

≥95% (HPLC)

• Sinonimo/i: β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate
• Formula empirica (notazione di Hill): C₁₁H₁₅N₂O₈P
• Numero CAS: 1094-61-7
• Peso molecolare: 334.22
• Beilstein: 3570187
• Numero CE: 214-136-5
• Numero MDL: MFCD00038748
• Codice UNSPSC: 41106305
• ID PubChem: 24897645
• NACRES: NA.51

Proprietà

• Saggio: ≥95% (HPLC); ≥95% (spectrophotometric assay)
• Stato: powder
• Solubilità: H₂O: soluble-50 mg/mL to clear, colorless to faintly yellow
• Temperatura di conservazione: −20°C
• Stringa SMILE: C[C@H]1[C@@H](C)[C@@H](O[C@@H]1COP(O)([O-])=O)[n+]2cccc(c2)C(N)=O
• InChI: 1S/C13H19N2O6P/c1-8-9(2)13(21-11(8)7-20-22(17,18)19)15-5-3-4-10(6-15)12(14)16/h3-6,8-9,11,13H,7H2,1-2H3,(H3-,14,16,17,18,19)/t8-,9+,11+,13+/m0/s1; YYNOOWWEYJELSF-SEMCEJNYSA-N

Descrizione

Descrizione generale

β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

Applicazioni

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Altre note

Note: This is the common form of NMN. Do not confuse it with α-NMN.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)