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878112P

Avanti

C16-18:1 PC

Avanti Research™ - A Croda Brand 878112P, powder

Sinonimo/i:

1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine

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About This Item

Formula empirica (notazione di Hill):
C42H84NO7P
Numero CAS:
95403-34-2
Peso molecolare:
746.09
Numero MDL:
MFCD11974148
Codice UNSPSC:
12352211
NACRES:
NA.25

Stato

powder

Confezionamento

pkg of 1 × 5 mg (878112P-5mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 878112P

Tipo di lipide

bioactive lipids
phosphoglycerides

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COCCCCCCCCCCCCCCCC)=O

InChI

SIEDNCDNGMIKST-IYEJTHTFSA-N

Categorie correlate

Descrizione generale

C16-18:1 PC, also called as 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine (HOPC), is a member of platelet-activating factor (PAF) family of glycerophospholipids. HOPC is a mono-ether PC containing ester-linked 18:1 chain (oleoyl) at the sn-2 position and an ether-linked 16:0 chain (hexadecyl) at the sn-1 position.

Applicazioni

C16-18:1 PC or 1-O-hexadecyl-2-oleoyl-sn-glycero-3-phosphocholine may be used in the liposome binding assay. It may also be used as a lipid standard for quantification of glycerophosphocholine by liquid chromatography–mass spectrometry (LC–MS).

Azioni biochim/fisiol

Platelet-activating factor (PAF), a lipid mediator acts as a pro-inflammatory agent that exhibits variety of biological and pharmacological effects.

Confezionamento

5 mL Clear Glass Sealed Ampule (878112P-5mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

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Certificati d'analisi (COA)

Lot/Batch Number

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Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform
John J H Shin et al.
Developmental cell, 52(4), 461-476 (2020-01-14)
Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain phosphomonoesters in their headgroups having pKa values in the physiological range. The phosphomonoester headgroup of phosphatidic acid enables this lipid to act as

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