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Documenti fondamentali

840034P

Avanti

16:0-18:1 PS (POPS)

Avanti Research - A Croda Brand

Sinonimo/i:

1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); POPS; PS(16:0/18:1(9Z)); 110669

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About This Item

Formula empirica (notazione di Hill):
C40H75NO10PNa
Numero CAS:
Peso molecolare:
783.99
Numero MDL:
Codice UNSPSC:
51191904
NACRES:
NA.25

Descrizione

1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Saggio

>99% (TLC)

Stato

powder

Confezionamento

pkg of 1 × 10 mg (840034P-10mg)
pkg of 2 × 100 mg (840034P-200mg)
pkg of 5 × 100 mg (840034P-500mg)
pkg of 1 × 25 mg (840034P-25mg)

Produttore/marchio commerciale

Avanti Research - A Croda Brand

Tipo di lipide

phospholipids
cardiolipins

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Stringa SMILE

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

RQYKXRYGZHMUSU-JEAFVVATSA-M

Descrizione generale

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Applicazioni

16:0-18:1 PS (POPS) has been used:
  • in phospholipid mixture for nanodisc preparation
  • in liposome preparation
  • in lipid vesicle preparation for surface plasmon resonance (SPR) analysis

Azioni biochim/fisiol

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the ability to create new memories, to focus attention, to reason and solve problems and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Confezionamento

5 mL Clear Glass Sealed Ampule (840034P-10mg)
5 mL Clear Glass Sealed Ampule (840034P-200mg)
5 mL Clear Glass Sealed Ampule (840034P-25mg)
5 mL Clear Glass Sealed Ampule (840034P-500mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Cellular phosphatase activity of C1-Ten/Tensin2 is controlled by Phosphatidylinositol-3, 4, 5-triphosphate binding through the C1-Ten/Tensin2 SH2 domain
Kim E, et al.
Cellular Signalling, 51, 130-138 (2018)
Fluorophore Labeling, Nanodisc Reconstitution and Single-molecule Observation of a G Protein-coupled Receptor
Lamichhane R, et al.
Bio-protocol, 7(12) (2017)
Josef Melcr et al.
Journal of chemical theory and computation, 16(1), 738-748 (2019-11-26)
Phosphatidylserine (PS) lipids are important signaling molecules and the most common negatively charged lipids in eukaryotic membranes. The signaling can be often regulated by calcium, but its interactions with PS headgroups are not fully understood. Classical molecular dynamics (MD) simulations
Carina Drechsler et al.
Biophysical journal, 115(8), 1509-1517 (2018-09-30)
Lipid asymmetries between the outer and inner leaflet of the lipid bilayer exist in nearly all biological membranes. Although living cells spend great effort to adjust and maintain these asymmetries, little is known about the biophysical phenomena within asymmetric membranes
Examination of the Interaction between a Membrane Active Peptide and Artificial Bilayers by Dual Polarisation Interferometry
Payne JAE, et al.
Bio-protocol, 7(1), e2087-e2087 (2017)

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