840035P

18:1 PS (DOPS)

Avanti Research^™ - A Croda Brand

• Sinonimo/i: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine (sodium salt); DOPS; PS(18:1(9Z)/18:1(9Z))
• Formula empirica (notazione di Hill): C₄₂H₇₇NO₁₀PNa
• Numero CAS: 90693-88-2
• Peso molecolare: 810.03
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 10 mg (840035P-10mg); pkg of 2 × 100 mg (840035P-200mg); pkg of 5 × 100 mg (840035P-500mg); pkg of 1 × 25 mg (840035P-25mg)
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand
• Solubilità: soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H78NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/b19-17-,20-18-;/t38-,39+;/m1./s1; KPHZNDUWYZIXFY-YORIBCANSA-M

Descrizione

Descrizione generale

DOPS is an excellent substitute for the naturally occurring Brain PS. It has similar physical properties and is more stable to oxidation. DOPS has been used, along with DOPC and DOPE, in lipid mixtures to mimic platelet membranes for coagulation studies.

Phosphoserine/phosphatidylserine (PS) is an endogenous phospholipid, that is found in all polyanionic macromolecules.

Applicazioni

18:1 PS (DOPS) has been used:

• in liposomes (multi-lamellar vesicles) preparation
• as a component in incubation buffer to measure exosomes associated procoagulant activity
• in the preparation of lipid vesicles

Azioni biochim/fisiol

Phosphoserine (PS) can be used as a template for the recognition of cancer antigen 125 (CA 125). It is very essential for healthy nerve cell membranes and myelin. Exogenous PS can be actively absorbed in humans. It has the ability to cross the blood-brain barrier. It plays a key role in the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories and several other cognitive activities. It actively participates in the locomotor functions, like rapid reactions and reflexes.

Confezionamento

5 mL Clear Glass Sealed Ampule (840035P-10mg)

5 mL Clear Glass Sealed Ampule (840035P-200mg)

5 mL Clear Glass Sealed Ampule (840035P-25mg)

5 mL Clear Glass Sealed Ampule (840035P-500mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3