900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinonimo/i: Formyl sulfonyl fluoride TMS-Alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₂H₁₃FO₃SSi
• Numero CAS: 2088829-01-8
• Peso molecolare: 284.38
• Codice UNSPSC: 12352200
• NACRES: NA.22

Proprietà

• Saggio: ≥95%
• Forma fisica: powder or crystals
• Impiego in reazioni chimiche: reaction type: click chemistry
• Temperatura di conservazione: −20°C
• Stringa SMILE: O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

Descrizione

Applicazioni

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifunctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable