900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• Sinonimo/i: Bromo sulfonyl fluoride alkyne, Probe building block
• Formula empirica (notazione di Hill): C₁₂H₁₄BrFO₂SSi
• Numero CAS: 2088829-12-1
• Peso molecolare: 349.29
• Numero MDL: MFCD30737997
• Codice UNSPSC: 12352200
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: ≥95%
• Stato: solid
• Impiego in reazioni chimiche: reaction type: click chemistry
• Temperatura di conservazione: −20°C
• Stringa SMILE: [Si](C)(C)(C)C#Cc1cc(cc(c1)CBr)[S](=O)(=O)F
• InChI: 1S/C12H14BrFO2SSi/c1-18(2,3)5-4-10-6-11(9-13)8-12(7-10)17(14,15)16/h6-8H,9H2,1-3H3; QSYGHPYMWBAJRL-UHFFFAOYSA-N

Descrizione

Applicazioni

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Altre note

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable