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757810

Sigma-Aldrich

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid

average Mn 1,000 (n~22), cross-linking reagent amine reactive, cross-linking reagent thiol reactive

Sinonimo/i:

Polyethylene glycol, mercaptoPEG acid, mercaptopoly(ethylene glycol) carboxylic acid, mercaptopolyoxyethylene acetic acid, thio-PEG, thiol-PEG-acid, thiol-PEG-carboxylate

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About This Item

Formula condensata:
HSC2H4O(C2H4O)nCH2CO2H
Numero CAS:
Numero MDL:
Codice UNSPSC:
12162002
NACRES:
NA.23

Nome del prodotto

Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid, average Mn 1,000

Stato

solid

PM

PEG average Mn 1,000 (n~22)
average Mn 1,000

Impiego in reazioni chimiche

reagent type: cross-linking reagent
reactivity: amine reactive

reagent type: cross-linking reagent
reactivity: thiol reactive

Temp. transizione

Tm 40-45 °C

Estremità Ω

thiol

Estremità α

carboxylic acid

Architettura del polimero

shape: linear
functionality: heterobifunctional

Temperatura di conservazione

−20°C

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Applicazioni

  • bioconjugation
  • drug delivery
  • PEG hydrogel
  • crosslinker
  • surface functionalization
Reported applications include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

>604.4 °F

Punto d’infiammabilità (°C)

> 318 °C


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S M Barber et al.
The journal of physical chemistry. A, 110(13), 4538-4542 (2006-03-31)
We have developed an efficient method for producing difunctional, bilateral nanospheres. A monolayer of nanoparticles was prepared followed by deposition of a thin layer of metal. By varying the base particle and metal deposited, bilateral nanoparticles were formed. The different
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De Vos, K.; et al.
Biosensors And Bioelectronics, 24, 2525-2533 (2009)
Eunjung Kim et al.
Biomaterials, 31(16), 4592-4599 (2010-03-09)
We investigated the synergism between shRNAs against Bcl-xL and doxorubicin (DOX) using aptamer-conjugated polyplexes (APs) in combination cancer therapy. Synergistic and selective cancer cell death was achieved by AP-mediated co-delivery of very small amounts of DOX and Bcl-xL-specific shRNA, which

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Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.