QBD10850

Thiol-dPEG^®₁₂-acid

>95% (HPLC)

• Sinonimo/i: CT(PEG)₁₂, Carboxy-PEG-Thiol, Carboxy-PEG₁₂-Thiol, HS-PEG₁₂-COOH, Thiol-PEG₁₂-acid
• Formula empirica (notazione di Hill): C₂₇H₅₄O₁₄S
• Peso molecolare: 634.77
• Numero MDL: MFCD21363238
• Codice UNSPSC: 12162002
• NACRES: NA.22

Proprietà

• Saggio: >95% (HPLC)
• Stato: solid or viscous liquid
• Impiego in reazioni chimiche: reaction type: Pegylations
• Architettura del polimero: shape: linear; functionality: heterobifunctional
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Caratteristiche e vantaggi

Thiol-dPEG₁₂-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long.

Note legali

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable