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729159

Sigma-Aldrich

Poly(ethylene glycol) methyl ether thiol

average MN 6,000, chemical modification reagent thiol reactive, methoxy, thiol

Sinonimo/i:

Polyethylene glycol, Methoxy PEG thiol, Methoxypolyethylene glycol thiol, PEG thiol, mPEG thiol

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About This Item

Formula condensata:
CH3O(CH2CH2O)nCH2CH2SH
Codice UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether thiol, average Mn 6,000

Forma fisica

solid

Livello qualitativo

100

PM

average Mn 6,000

Impiego in reazioni chimiche

reagent type: chemical modification reagent
reactivity: thiol reactive

Punto di fusione

56-61 °C

Mw/Mn

≤1.2

Estremità Ω

thiol

Estremità α

methoxy

Architettura del polimero

shape: linear
functionality: monofunctional

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

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Descrizione generale

Poly(ethylene glycol) methyl ether thiol (mPEGthiol) is a thiol-terminated biocompatible polymer widely used in the surfacefunctionalization of gold nanoparticles. Thiol moieties bind with high affinityto gold surfaces by forming a self-assembled monolayer (SAM) through thecovalent thiolate–metal bond. mPEG thiol-coated Au nanoparticles findapplication in the fields of biosensors and drug delivery systems.

Applicazioni

Poly(ethylene glycol) methyl ether thiol-coated Au nanoparticles can be used for the determination of melamine T. by an optical method. It can also be used to fabricate switchable super-wetting membranes foroil/water separation.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCL4582
MKCH0719
MKCF5112
MKBW7623V
MKBS3186V

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Articoli

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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