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323446

Sigma-Aldrich

Ammonium tetrathiomolybdate

99.97% trace metals basis

Sinonimo/i:

Ammonium thiomolybdate, Diammonium tetrathiomolybdate

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About This Item

Formula condensata:
(NH4)2MoS4
Numero CAS:
15060-55-6
Peso molecolare:
260.28
Numero MDL:
MFCD00136013
Codice UNSPSC:
12352302
ID PubChem:
24859366
NACRES:
NA.23

Livello qualitativo

100

Saggio

99.97% trace metals basis

Forma fisica

crystalline

Impiego in reazioni chimiche

reagent type: catalyst
core: molybdenum

Impurezze

≤350.0 ppm Trace Metal Analysis

Punto di fusione

>300 °C (lit.)

Stringa SMILE

[NH4+].[NH4+].[S-][Mo]([S-])(=S)=S

InChI

1S/Mo.2H3N.4S/h;2*1H3;;;;/q;;;;;2*-1/p+2
PQNOIAHNKHBLRN-UHFFFAOYSA-P

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Categorie correlate

Applicazioni

Ring opening of aziridines leading to sulfides and disulfides.
This classic building block for transition metal sulfide cluster compounds was recently used in a low-temperature, solid state synthesis of a new series of heterometallic sulfide clusters stabilized with dppm [bis(diphenylphosphino)methane] ligands.

Azioni biochim/fisiol

Acts as a chelator in vivo to reduce copper levels. Tetrathiomolybdate interferes with angiogenesis and reduces tumor growth. Its mechanism may involve inhibition of NF-κB and downstream cytokines.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
MKCQ4519
MKCM4844
MKCK3064
MKCJ8657
MKCG8991

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Satoru Yamasaki et al.
The Journal of cell biology, 177(4), 637-645 (2007-05-16)
Zinc is an essential trace element required for enzymatic activity and for maintaining the conformation of many transcription factors; thus, zinc homeostasis is tightly regulated. Although zinc affects several signaling molecules and may act as a neurotransmitter, it remains unknown
George J Brewer
Current cancer drug targets, 5(3), 195-202 (2005-05-17)
Tetrathiomolybdate (TM) is a novel anticopper agent under development for use in Wilson's disease. It acts by forming a stable tripartite complex with serum albumin and copper, rendering the complexed copper unavailable for cellular uptake. TM is a very potent
Yu Cheng et al.
Molecular pharmaceutics, 16(8), 3489-3501 (2019-06-28)
Recently, multifunctional clearable inorganic theranostic nanoparticles have been attracting more and more attention. Protein-based nanoparticles can be cleared by the hepatobiliary system efficiently. In this work, ultrasmall gadolinium oxide (Gd2O3) nanoparticles, which possess the advantage of high longitudinal relaxation rate
Zhe Chen et al.
Langmuir : the ACS journal of surfaces and colloids, 34(4), 1635-1644 (2018-01-02)
Wear occurs between two rubbing surfaces. Severe wear due to seizure under high pressure leads to catastrophic failures of mechanical systems and raises wide concerns. In this paper, a kind of synthetic oil-soluble ultrathin MoS
Devarajulu Sureshkumar et al.
The Journal of organic chemistry, 72(6), 2106-2117 (2007-02-24)
A comprehensive study of a general and effective one-step procedure for the synthesis of beta-sulfonamidodisulfides directly from N-tosyl aziridines in a regio- and stereospecific manner under neutral conditions without the use of any Lewis acid or base has been reported.
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