249505

2,6-Di-tert-butyl-4-methylpyridine

98%

• Sinonimo/i: 2,6-Bis(1,1-dimethylethyl)-4-methylpyridine, 2,6-Bis(tert-butyl)-4-methylpyridine, 2,6-Ditert-butyl-4-methylpyridine, 4-Methyl-2,6-di-tert-butylpyridine
• Formula empirica (notazione di Hill): C₁₄H₂₃N
• Numero CAS: 38222-83-2
• Peso molecolare: 205.34
• Beilstein: 130503
• Numero CE: 253-834-4
• Numero MDL: MFCD00006305
• Codice UNSPSC: 12352100
• ID PubChem: 24855001
• NACRES: NA.22

Proprietà

• Livello qualitativo: 200
• Saggio: 98%
• Stato: solid
• Indice di rifrazione: n20/D 1.4763 (lit.)
• P. ebollizione: 233 °C (lit.)
• Punto di fusione: 33-36 °C (lit.)
• Solubilità: ethanol: soluble 5%, clear to slightly hazy, colorless to dark yellow
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Cc1cc(nc(c1)C(C)(C)C)C(C)(C)C
• InChI: 1S/C14H23N/c1-10-8-11(13(2,3)4)15-12(9-10)14(5,6)7/h8-9H,1-7H3; HVHZEKKZMFRULH-UHFFFAOYSA-N

Descrizione

Descrizione generale

2,6-Di-tert-butyl-4-methylpyridine is a sterically hindered, non-nucleophilic base which distinguishes between BrÖnsted (protonic) and Lewis acids. It also enables the direct high-yield conversion of aldehydes and ketones to vinyl triflates. It inhibits desilylation and hydration of the products during GaCl₃-catalyzed ortho-ethynylation of phenol.

Applicazioni

2,6-Di-tert-butyl-4-methylpyridine has been used:

• in the synthesis of 1,2-dihydro-2-silanaphthalene derivatives
• as base in PtCl₄-catalyzed cyclization reactions of homopropargyl azide derivatives
• diastereoselective synthesis of β-thiomannopyranosides

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H315,H319,H335
• Consigli di prudenza: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): 183.2 °F - closed cup
• Punto d’infiammabilità (°C): 84 °C - closed cup
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves