1297001

人绒毛膜促性腺激素

United States Pharmacopeia (USP) Reference Standard

• 别名: 绒毛膜促性腺激素 人, HCG, 绒毛膜促性腺激素
• CAS号: 9002-61-3
• MDL號碼: MFCD00130797
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: gonadotropin
• 分子量: 37.9 kDa
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: −20°C

说明

一般說明

由 92 个氨基酸 α 链组成的糖蛋白激素，与 LH、FSH 和 TSH 相同； 和一个独特的 149 个氨基酸 β 链。由绒毛膜组织产生，负责在妊娠早期维持黄体。也由滋养层细胞肿瘤产生，其特征是游离 hCG β-链升高和高糖基化 hCG。

本产品按照现行药典要求提供和指定。所有本产品相关的支持信息，包括 SDS 和任何产品信息宣传册，均是在药典的授权下制定和发布的。
如需进一步信息和支持，请访问现行药典网站。

應用

• Comprehensive Prenatal Screening: Human chorionic gonadotropin (hCG) is crucial in combined first-trimester screening and invasive diagnostics for chromosomal aberrations, offering insights into prenatal health and improving detection rates compared with non-invasive prenatal testing (NIPT). This underscores hCG′s vital role in early gestational health assessments (Gadsbøll et al., 2024).


• Twin Pregnancy Outcomes: hCG levels are studied for their association with adverse outcomes in twin gestations, providing valuable data for managing and monitoring high-risk pregnancies. This research highlights hCG′s predictive value in obstetrics, aiding in the anticipatory management of potential complications (Yamasato and Ono, 2024).


• Missed Abortion Treatment: The effectiveness of Nigella sativa oil, influenced by hCG levels, on the outcomes of missed abortions is explored through a randomized clinical trial. This study demonstrates the potential for integrating hCG monitoring into therapeutic strategies to improve pregnancy outcomes (Mohammadi et al., 2024).


• Germ Cell Testicular Tumor Biomarkers: The role of hCG as a biomarker in germ cell testicular tumors is examined, enhancing the understanding of tumor biology and improving diagnostic accuracy. This research is pivotal for developing targeted therapies and improving prognostic evaluations in oncology (Kılınç et al., 2024).


• Molar Cesarean Scar Ectopic Pregnancy: Studies involving hCG focus on its implications in rare cases of molar cesarean scar ectopic pregnancies, providing insights into unusual gestational complications. This research is crucial for developing guidelines and treatment protocols in exceptionally complex pregnancy cases (Hosseinimousa et al., 2024).

包裝

1 个样品瓶，每包 530 个 USP 单位

分析報告

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。

其他說明

该产品是美国药典生物制品计划的一部分。

可能适用相应的销售限制。

安全信息

• 象形圖: GHS08
• 訊號詞: Warning
• 危險聲明: H361
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable