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生物源
Porcine thyroid
品質等級
形狀
powder
分子量
~670 kDa
成份
Iodine, ≥0.3%
氮分析
14.0-17.5% total
技術
protein purification: suitable
灰分
≤4%
pI
4.58
UniProt登錄號
儲存溫度
−20°C
基因資訊
pig ... TG(100156471)
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生化／生理作用
甲状腺球蛋白已被证明可调节包括碘化钠同向转运蛋白和Pendrin在内的碘转运蛋白的转录。
甲状腺球蛋白是一种参与碘代谢的主要蛋白质。它由一种储存在甲状腺中的含碘蛋白质组成，当甲状腺受到垂体促甲状腺激素(TSH)的刺激时，就会转化为循环中的甲状腺素。甲状腺球蛋白常被用作产生抗体的载体蛋白。它作为载体蛋白的优势来自于其大量的酪氨酸残基，可以通过重氮反应进行偶联。
其他說明
电泳异构。
準備報告
用水 (20 mg/mL) 复溶时，观察到浑浊溶液和一些不溶物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
L D Kohn et al.
Trends in endocrinology and metabolism: TEM, 12(1), 10-16 (2001-01-04)
Iodide transport by thyrocytes involves porters on the apical and basal surfaces of the cell facing the follicular lumen and bloodstream, respectively. Recent work identifies pendrin as an apical porter and shows that follicular thyroglobulin is a transcriptional regulator of
Antibody production and immunocytochemical localization of amino acid transporters.
David V Pow et al.
Methods in molecular biology (Clifton, N.J.), 227, 213-244 (2003-06-26)
Sanathana Konugolu Venkata Sekar et al.
Scientific reports, 8(1), 10015-10015 (2018-07-04)
Thyroid plays an important role in the endocrine system of the human body. Its characterization by diffuse optics can open new path ways in the non-invasive diagnosis of thyroid pathologies. Yet, the absorption spectra of tyrosine and thyroglobulin-key tissue constituents
C Nascimento et al.
European journal of endocrinology, 169(5), 689-693 (2013-08-14)
Thyroglobulin (Tg) measurement is a major tool for the follow-up of differentiated thyroid cancer (DTC) patients; however, in patients who do not undergo radioactive iodine (RAI) ablation, normal ultrasensitive Tg levels measured under levothyroxine treatment (usTg/l-T4) are not well defined.
Rodrigo Moreno-Reyes et al.
The Journal of clinical endocrinology and metabolism, 98(9), 3694-3701 (2013-07-13)
Many countries in Europe remain mildly iodine deficient but relatively few country-level data exist on mild iodine deficiency (MID) and its impact on thyroid function in pregnant women. To determine the prevalence of thyroid disorders in pregnant women in Belgium
商品
With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance.
With the emergence of mass spectrometry for the clinical measurement of proteins in biological matrices, the development of biological reference materials will continue to grow in importance.
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