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A9165

Sigma-Aldrich

N-乙酰基-L-半胱氨酸

≥99% (TLC), suitable for cell culture, BioReagent

别名:

LNAC, NAC

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About This Item

线性分子式:
HSCH2CH(NHCOCH3)CO2H
CAS号:
616-91-1
分子量:
163.19
Beilstein:
1724426
EC號碼:
210-498-3
MDL號碼:
MFCD00004880
分類程式碼代碼:
12352209
PubChem物質ID:
24891402
NACRES:
NA.26

product name

N-乙酰基-L-半胱氨酸, BioReagent, suitable for cell culture

產品線

BioReagent

品質等級

200

化驗

≥99% (TLC)

形狀

powder

技術

cell culture | mammalian: suitable

顏色

white to off-white

mp

106-108 °C (lit.)

溶解度

H2O: 100 mg/mL (with heating)

儲存溫度

2-8°C

SMILES 字串

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI 密鑰

PWKSKIMOESPYIA-BYPYZUCNSA-N

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應用

N-乙酰-L-半胱氨酸已被用作小鼠肠道干细胞培养的肠道基础培养基的组成部分，也被用作膨胀培养基的组成部分。

生化／生理作用

抗氧化剂和黏液溶解剂(mucolytic agent)。增加细胞池的自由基清除剂。 据报道可防止神经细胞凋亡，但会诱导平滑肌细胞凋亡。抑制HIV复制。可作为微粒体谷胱甘肽转移酶的底物。

其他說明

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

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产品编号
说明
价格

應用

产品编号
说明
价格

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H319

危險分類

Eye Irrit. 2

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Jing Xie et al.
Bone research, 7, 23-23 (2019-10-28)
Osteoarthritis (OA) is an age-related disorder that is strongly associated with chondrocyte senescence. The causal link between disruptive PTEN/Akt signaling and chondrocyte senescence and the underlying mechanism are unclear. In this study, we found activated Akt signaling in human OA
Meritxell Huch et al.
Nature, 494(7436), 247-250 (2013-01-29)
The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomach and hair follicles. A three-dimensional culture system allows long-term clonal expansion of single Lgr5(+) stem
Suzanne M Cloonan et al.
Journal of medicinal chemistry, 58(11), 4494-4505 (2015-05-12)
Ruthenium polypyridyl complexes show great promise as new photodynamic therapy (PDT) agents. However, a lack of detailed understanding of their mode of action in cells poses a challenge to their development. We have designed a new Ru(II) PDT candidate that
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