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Merck

SRE0041

Sigma-Aldrich

来自牛肝的过氧化氢酶

Suitable for manufacturing of diagnostic kits and reagents, lyophilized powder, 2,000-5,000 units/mg protein

别名:

过氧化氢酶 来源于牛肝脏, H2O2:H2O2 氧化还原酶

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

品質等級

形狀

lyophilized powder

比活性

2,000-5,000 units/mg protein

分子量

tetramer ~250 kDa

等電點

5.4

應用

diagnostic assay manufacturing

運輸包裝

wet ice

儲存溫度

−20°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI 密鑰

NUVBSKCKDOMJSU-UHFFFAOYSA-N

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一般說明

Research Area: Cell Signaling

Catalase from bovine liver is a tetramer consisting of 4 equal subunits each with a 60 kDa molecular weight. Each of these subunits contains iron bound to a protoheme IX group. The enzyme will also strongly bind to NADP, where NADP and the heme group are within 13.7 angstroms.

應用

过氧化氢酶作为天然抗氧化剂,可用于研究活性氧物质对基因表达和凋亡的作用。它还被用于保护蛋白质、脂质和核酸免受氧化损伤。 工业上,过氧化氢酶已被用于去除添加至牛奶和奶酪中以及纺织品漂白使用的过氧化氢,并用于检查其对DNA修复大肠杆菌突变体活力的阳性效应。

生化/生理作用

Catalase, an antioxidant enzyme found in all aerobic organisms, catalyzes the degradation of hydrogen peroxide, a byproduct of metabolic processes, into less harmful water and oxygen. It can also react with alkylhydrogen peroxides, such as methylperoxide and ethylperoxide and the second H2O2 molecule can be replaced by methanol, ethanol, propanol, formate and nitrate as a hydrogen donor. Catalase enzyme uses either iron (Fe) or manganese (Mn) as cofactor, and are classified as Fe-CAT or Mn-CAT.

單位定義

在pH 7.0、25摄氏度下,一个单位每分钟分解1.0微摩尔的过氧化氢,而过氧化氢的浓度则从10.3降至9.2毫摩尔。

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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