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Merck

W224847

Sigma-Aldrich

4-萜烯醇

≥95%, FCC, FG

别名:

4-松油烯醇

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About This Item

经验公式(希尔记法):
C10H18O
CAS号:
分子量:
154.25
FEMA號碼:
2248
EC號碼:
歐洲委員會號碼:
2229
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
2.072
NACRES:
NA.21

生物源

synthetic

品質等級

等級

FG
Halal

法律遵循

EU Regulation 1334/2008 & 872/2012
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

化驗

≥95%

折射率

n20/D 1.478

bp

88-90 °C

密度

0.931 g/mL at 25

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

感官的

woody; earthy; pepper

SMILES 字串

CC(C)C1(O)CCC(C)=CC1

InChI

1S/C10H18O/c1-8(2)10(11)6-4-9(3)5-7-10/h4,8,11H,5-7H2,1-3H3

InChI 密鑰

WRYLYDPHFGVWKC-UHFFFAOYSA-N

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一般說明

自然发生: 茴香,罗勒,黑加仑,可可,香菜,蔓越莓,葡萄柚,柠檬,酸橙,马郁兰,薄荷油,肉豆蔻和留兰香。

應用

  • 4-松油醇通过p38MAPK/NF-B信号通路轴(signaling pathway axis)抑制IL-13和粘液产生,从而改善小鼠变应性鼻炎和哮喘综合征。: 展示了4-松油醇在呼吸系统疾病治疗中的抗炎和治疗潜力,突出了其在分子水平上的作用机制(Bezerra Barros et al., 2020)。

生化/生理作用

味道 30ppm

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Antonella Casiraghi et al.
Pharmaceutical development and technology, 15(5), 545-552 (2009-10-22)
This work aimed to evaluate the effect induced by excipients conventionally used for topical dosage forms, namely isopropyl myristate (IPM) or oleic acid (OA) or polyethylene glycol 400 (PEG400) or Transcutol (TR), on the human skin permeability of terpinen-4-ol (T4OL)
Risa Haigou et al.
Journal of oleo science, 61(1), 35-43 (2011-12-23)
We examined the in vitro metabolism of (+)-terpinen-4-ol by human liver microsomes and recombinant enzymes. The biotransformation of (+)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry (GC-MS). (+)-Terpinen-4-ol was found to be oxidized to (+)-(1R,2S,4S)-1,2-epoxy-p-menthan-4-ol, (+)-(1S,2R,4S)-1,2-epoxy-p-menthan-4-ol, and (4S)-p-menth-1-en-4,8-diol by human liver
Mi-Jin Park et al.
Journal of microbiology (Seoul, Korea), 48(4), 496-501 (2010-08-28)
In this study, the antibacterial activity of essential oil from Chamaecyparis obtusa (Sieb. et Zucc) leaves and twigs was investigated. The test strains were Klebsiella pneumoniae, Listeria monocytogenes, Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, Legionella pneumophila, and Methicilline-resistant Staphylococcus aureus.
C Njume et al.
International journal of antimicrobial agents, 38(4), 319-324 (2011-07-15)
The aim of this study was to isolate and identify phytochemicals with anti-Helicobacter pylori activity from the stem bark of Sclerocarya birrea. The plant crude extract was fractionated by silica gel column and thin layer chromatography techniques, initially with ethyl
Kotchaphan Chooluck et al.
Planta medica, 78(16), 1761-1766 (2012-10-03)
The purpose of this study was to investigate dermal pharmacokinetics of terpinen-4-ol in rats following topical administration of plai oil derived from the rhizomes of Zingiber cassumunar Roxb. Unbound terpinen-4-ol concentrations in dermal tissue were measured by microdialysis. The dermal

Global Trade Item Number

货号GTIN
W224847-1KG4061838248930
W224847-250G4061837509063
W224847-5KG
W224847-SAMPLE4061838191243

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